SCHEMBL24176901

SCHEMBL24176901

CC(C)Oc1ccc(-c2nc(-c3ccc(CN4CCC(C(=O)O)CC4)c4ccccc34)no2)cc1C#N

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 20/20 0.60
S1PR5 Q9H228 5/20 0.55
S1PR3 Q99500 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30439030 1.00 S1PR1 (0.60) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL25168548 0.99 S1PR1 (0.60) S1PR1S1PR5S1PR3
SCHEMBL24176978 0.96 S1PR1 (0.61) S1PR1S1PR5S1PR3
SCHEMBL30439244 0.96 S1PR1 (0.61) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL25174473 0.95 S1PR1 (0.60) S1PR1S1PR5S1PR3
SCHEMBL30438809 0.93 S1PR1 (0.62) S1PR1S1PR5S1PR3
SCHEMBL24176950 0.93 S1PR1 (0.62) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL31085584 0.93 S1PR1 (0.62) S1PR1S1PR5S1PR3
Hydrochloric Acid SCHEMBL25167021 0.93 S1PR1 (0.62) S1PR1S1PR5S1PR3
SCHEMBL24176909 0.92 S1PR1 (0.59) S1PR1S1PR5S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4177255-A1 OXADIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2023-05-10 EP disclosed
WO-2022002078-A1 OXADIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF 中国科学院上海药物研究所 2022-01-06 WO disclosed