Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.62 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.57 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24176950 | 1.00 | S1PR1 (0.62) | S1PR1S1PR3S1PR5MAP4K4MINK1 | |
| Hydrochloric Acid SCHEMBL25167021 | 0.99 | S1PR1 (0.62) | S1PR1S1PR3S1PR5MAP4K4MINK1 | |
| Hydrochloric Acid SCHEMBL31085584 | 0.99 | S1PR1 (0.62) | S1PR1S1PR3S1PR5MAP4K4MINK1 | |
| SCHEMBL30439244 | 0.95 | S1PR1 (0.61) | S1PR1S1PR3S1PR5 | |
| SCHEMBL24176978 | 0.95 | S1PR1 (0.61) | S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL25174473 | 0.94 | S1PR1 (0.60) | S1PR1S1PR3S1PR5 | |
| SCHEMBL24176899 | 0.94 | S1PR1 (0.55) | S1PR1S1PR3S1PR5 | |
| SCHEMBL30438813 | 0.94 | S1PR1 (0.59) | S1PR1S1PR3S1PR5 | |
| SCHEMBL24176909 | 0.94 | S1PR1 (0.59) | S1PR1S1PR3S1PR5 | |
| SCHEMBL24176901 | 0.93 | S1PR1 (0.60) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208954-A1 | OXADIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2024-06-27 | — | — | US | claimed |
| EP-4177255-A1 | OXADIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-05-10 | — | — | EP | claimed |
| US-20240208954-A1 | OXADIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2024-06-27 | — | — | US | disclosed |
| EP-4177255-A1 | OXADIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208954-A1 | OXADIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SUCNR1, GPR35, P2RY11 | S1PR1 26/4885S1PR3 12/4885S1PR5 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.