⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14195896 | 0.79 | — | — | |
| SCHEMBL6686739 | 0.79 | — | — | |
| SCHEMBL6675135 | 0.79 | — | — | |
| SCHEMBL25009059 | 0.79 | — | — | |
| SCHEMBL19638604 | 0.79 | — | — | |
| SCHEMBL6689650 | 0.79 | — | — | |
| SCHEMBL25221983 | 0.79 | — | — | |
| SCHEMBL25221985 | 0.79 | — | — | |
| SCHEMBL22029812 | 0.79 | — | — | |
| SCHEMBL240568 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002242-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (HK) | 2022-01-06 | — | — | US | disclosed |
| US-20170051041-A1 | FACTOR VIII B CELL EPITOPE VARIANTS HAVING REDUCED IMMUNOGENICITY | BLOODWORKS | 2017-02-23 | — | — | US | disclosed |