Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARD | Q03181 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180069 | 0.81 | AR (0.47) | PPARDALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL22390440 | 0.81 | NTRK1 (0.40) | NTRK1ALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL3291252 | 0.80 | MAPT (0.46) | NTRK1ALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL22957698 | 0.79 | SLC6A4 (0.56) | NTRK1ALDH1A1 | |
| SCHEMBL12844526 | 0.79 | HMGCR (0.53) | KDM4EHMGCRGABRA1GABRB2 | |
| SCHEMBL22957928 | 0.77 | NTRK1 (0.41) | NTRK1ALDH1A1KDM4EMEN1USP2 | |
| SCHEMBL14409249 | 0.76 | SSTR4 (0.46) | ALDH1A1KDM4EMEN1USP2HSP90AA1 | |
| SCHEMBL22957691 | 0.76 | NTRK1 (0.44) | NTRK1ALDH1A1MRGPRX1RAB9ACYP1A2 | |
| SCHEMBL22957708 | 0.76 | NTRK1 (0.42) | NTRK1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL16797594 | 0.75 | HTR1A (0.53) | ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704118-B1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-01-12 | — | — | EP | disclosed |