Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24067349 | 0.87 | CNR1 (0.43) | CNR1CNR2IL1BP2RX7ALDH1A1 | |
| SCHEMBL24067300 | 0.79 | IL1B (0.49) | CNR1CNR2IL1BP2RX7ALDH1A1 | |
| SCHEMBL24067327 | 0.79 | CNR1 (0.46) | CNR1CNR2IL1BP2RX7ALDH1A1 | |
| SCHEMBL24488604 | 0.78 | CNR1 (0.40) | CNR1CNR2IL1BP2RX7ALDH1A1 | |
| SCHEMBL24067351 | 0.78 | CNR1 (0.40) | CNR1CNR2IL1BP2RX7ALDH1A1 | |
| SCHEMBL22663740 | 0.78 | CNR1 (0.41) | CNR1CNR2IL1BP2RX7ALDH1A1 | |
| SCHEMBL24488602 | 0.77 | CNR1 (0.47) | CNR1CNR2AVPR1A | |
| SCHEMBL24067389 | 0.74 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL24067347 | 0.74 | CNR1 (0.44) | CNR1CNR2 | |
| SCHEMBL22450602 | 0.74 | CNR1 (0.44) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3936126-A1 | COMBINATION OF IAP INHIBITOR AND IMMUNE CHECKPOINT INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-01-12 | — | — | EP | disclosed |