SCHEMBL24183149

SCHEMBL24183149

CC(C)=CCC/C(C)=C/CC/C(C)=C/COc1cc(OC/C=C(\C)CC/C=C(\C)CCC=C(C)C)cc(OC/C=C(\C)CC/C=C(\C)CCC=C(C)C)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 7/20 0.58
TDP1 Q9NUW8 2/20 0.58
MAPT P10636 4/20 0.56
ALDH1A1 P00352 3/20 0.56
CYP3A4 P08684 2/20 0.56
KDM4E B2RXH2 1/20 0.56
NDUFS8 O00217 1/20 0.56
COXFA4 O00483 1/20 0.56
NDUFAB1 O14561 1/20 0.56
NDUFA1 O15239 1/20 0.56
NDUFS4 O43181 1/20 0.56
NDUFB5 O43674 1/20 0.56
NDUFB3 O43676 1/20 0.56
NDUFC1 O43677 1/20 0.56
NDUFA2 O43678 1/20 0.56
NDUFS5 O43920 1/20 0.56
NDUFS7 O75251 1/20 0.56
NDUFS2 O75306 1/20 0.56
NDUFS6 O75380 1/20 0.56
NDUFB1 O75438 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24183242 0.94 ALOX15 (0.53) ALOX15TDP1MAPTALDH1A1CYP3A4
SCHEMBL24183231 0.90 ALOX15 (0.60) ALOX15TDP1MAPTALDH1A1CYP3A4
SCHEMBL26582944 0.89 ALOX15 (0.61) ALOX15TDP1MAPTALDH1A1CYP3A4
SCHEMBL2943957 0.89 ALOX15 (0.61) ALOX15TDP1MAPTALDH1A1CYP3A4
SCHEMBL8577710 0.87 ALOX15 (0.60) ALOX15TDP1MAPTALDH1A1CYP3A4
SCHEMBL6654666 0.86 ALOX15 (0.51) ALOX15TDP1MAPTALDH1A1CYP3A4
SCHEMBL6653790 0.86 ALOX15 (0.51) ALOX15TDP1MAPTALDH1A1CYP3A4
SCHEMBL27464579 0.85 PTPN1 (0.52) ALOX15TDP1MAPTALDH1A1CYP3A4
SCHEMBL11757158 0.83 TRPV1 (0.56) ALOX15TDP1MAPTALDH1A1CYP3A4
SCHEMBL7536951 0.83 TRPV1 (0.56) ALOX15TDP1MAPTALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321228-A1 VACCINE ADJUVANTS AND METHODS OF SYNTHESIZING AND USING THE SAME EUAGORE, LLC 2023-10-12 US disclosed
US-20230321228-A1 VACCINE ADJUVANTS AND METHODS OF SYNTHESIZING AND USING THE SAME EUAGORE, LLC 2023-10-12 US disclosed
WO-2022011031-A1 VACCINE ADJUVANTS AND METHODS OF SYNTHESIZING AND USING THE SAME Amyris, Inc. (US) 2022-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321228-A1 VACCINE ADJUVANTS AND METHODS OF SYNTHESIZING AND USING THE SAME MYD88, TLR9, TLR5 ALOX15 59/4885TDP1 654/4885MAPT 2956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.