Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 6/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24183589 | 0.91 | ADRA2C (0.54) | ADRA2CHRH3KCNH2 | |
| SCHEMBL24183596 | 0.90 | ADRA2C (0.56) | ADRA2CHRH3KCNH2 | |
| SCHEMBL24183695 | 0.90 | ADRA2C (0.54) | ADRA2CHRH3KCNH2 | |
| SCHEMBL24183565 | 0.89 | ADRA2C (0.54) | ADRA2CHRH3KCNH2 | |
| SCHEMBL24183468 | 0.84 | ADRA2C (0.73) | ADRA2CHRH3KCNH2 | |
| SCHEMBL24183593 | 0.82 | ADRA2C (0.56) | ADRA2CHRH3KCNH2 | |
| SCHEMBL30359186 | 0.81 | ADRA2C (0.57) | ADRA2CHRH3 | |
| SCHEMBL24183660 | 0.81 | ADRA2C (0.57) | ADRA2CHRH3 | |
| SCHEMBL24183569 | 0.80 | ADRA2C (0.56) | ADRA2CHRH3 | |
| SCHEMBL24183686 | 0.80 | ADRA2C (0.56) | ADRA2CHRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008426-A1 | COMBINATION OF AN ALPHA2-ADRENOCEPTOR SUBTYPE C (ALPHA-2C) ANTAGONIST WITH A TASK1/3 CHANNEL BLOCKER FOR THE TREATMENT OF SLEEP APNEA | BAYER AKTIENGESELLSCHAFT (DE) | 2022-01-13 | — | — | WO | disclosed |