Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 13/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24184660 | 0.93 | CYP1A2 (0.46) | CYP2C9ACACBP2RY6LTA4HCHRNB2 | |
| SCHEMBL24184661 | 0.86 | NQO1 (0.50) | ACACBP2RY6KMT2A | |
| SCHEMBL9362384 | 0.86 | CYP2C9 (0.51) | CYP2C9P2RY6LTA4HCA12CA1 | |
| SCHEMBL16706066 | 0.84 | ACACB (0.57) | ACACBMEN1KMT2ALTA4HCHRNB2 | |
| SCHEMBL3434851 | 0.84 | ACACB (0.57) | ACACBMEN1KMT2ALTA4HCHRNB2 | |
| SCHEMBL26941807 | 0.82 | P2RY6 (0.34) | CYP2C9ACACBP2RY6MEN1KMT2A | |
| SCHEMBL28275779 | 0.80 | P2RY6 (0.40) | ACACBP2RY6CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL24184992 | 0.79 | ACACB (0.43) | ACACBMEN1KMT2ALTA4HCHRNB2 | |
| SCHEMBL91815 | 0.79 | APP (0.55) | ACACBP2RY6CA12CA1CA2 | |
| SCHEMBL24184976 | 0.79 | ACACB (0.49) | CYP2C9ACACBP2RY6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230313043-A1 | OPTICAL COMPONENT | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| US-20230313043-A1 | OPTICAL COMPONENT | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| WO-2022008474-A1 | OPTICAL COMPONENT | MERCK PATENT GMBH (DE) | 2022-01-13 | — | — | WO | disclosed |