Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25507466 | 0.90 | HRH3 (0.31) | HRH3 | |
| SCHEMBL22737182 | 0.89 | CYP1A2 (0.33) | HRH3L3MBTL3L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL25856032 | 0.87 | L3MBTL3 (0.33) | HRH3L3MBTL3L3MBTL1CYP1A2TSHR | |
| SCHEMBL24185483 | 0.86 | TSHR (0.33) | HRH3CYP1A2CYP2D6USP2TSHR | |
| SCHEMBL19370306 | 0.83 | CYP2D6 (0.39) | HRH3L3MBTL3L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL25814798 | 0.83 | CYP1A2 (0.33) | HRH3L3MBTL3L3MBTL1CYP1A2 | |
| SCHEMBL25518058 | 0.83 | HRH3 (0.34) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL26752530 | 0.83 | HRH3 (0.33) | HRH3 | |
| SCHEMBL25508404 | 0.82 | HRH3 (0.33) | HRH3KDM4EPOLB | |
| SCHEMBL26748933 | 0.82 | HRH3 (0.34) | HRH3L3MBTL3L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180427-A1 | COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |
| WO-2022111526-A1 | BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |
| WO-2022007903-A1 | COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF | 四川海思科制药有限公司 | 2022-01-13 | — | — | WO | disclosed |