Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13738909 | 0.91 | GSK3B (0.44) | ALDH1A1MAP2K4SMN1; SMN2NPSR1GSK3B | |
| SCHEMBL30349192 | 0.91 | GSK3B (0.44) | ALDH1A1MAP2K4SMN1; SMN2NPSR1GSK3B | |
| SCHEMBL15655636 | 0.88 | MAP2K4 (0.43) | ALDH1A1MAP2K4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15653909 | 0.88 | MAP2K4 (0.43) | ALDH1A1MAP2K4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15655491 | 0.87 | ADORA2A (0.42) | MAP2K4GSK3BHPGDGSK3AADORA2A | |
| SCHEMBL18401301 | 0.86 | GSK3B (0.39) | ALDH1A1MAP2K4SMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL18513164 | 0.86 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MEN1KMT2ANPSR1 | |
| SCHEMBL24186354 | 0.82 | ADORA1 (0.49) | ALDH1A1SMN1; SMN2GSK3BHPGDADORA2A | |
| SCHEMBL15685544 | 0.78 | HPGD (0.41) | ALDH1A1MAP2K4SMN1; SMN2NPSR1GSK3B | |
| SCHEMBL15656164 | 0.78 | GSK3B (0.41) | ALDH1A1SMN1; SMN2GSK3BHPGDGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011091-A1 | TREATMENT OF CANCER, INFLAMMATORY DISEASES AND AUTOIMMUNE DISEASES | USHER III INITIATIVE, INC. (US) | 2022-01-13 | — | — | WO | disclosed |