Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759799 | 0.95 | CRBN (0.53) | CRBNDDB1CSNK1A1 | |
| SCHEMBL31748857 | 0.95 | CRBN (0.53) | CRBNDDB1CSNK1A1 | |
| SCHEMBL20231475 | 0.88 | CRBN (0.52) | CRBNDDB1CSNK1A1ALDH2 | |
| SCHEMBL30906267 | 0.88 | CRBN (0.52) | CRBNDDB1CSNK1A1ALDH2 | |
| SCHEMBL28535858 | 0.85 | CRBN (0.54) | CRBNDDB1 | |
| SCHEMBL30689654 | 0.84 | IKZF2 (0.51) | CRBNDDB1CSNK1A1 | |
| SCHEMBL30741731 | 0.84 | CRBN (0.50) | CRBNDDB1CSNK1A1 | |
| SCHEMBL29753997 | 0.82 | CRBN (0.53) | CRBNDDB1CSNK1A1 | |
| SCHEMBL20046720 | 0.82 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL29614584 | 0.82 | CRBN (0.56) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257365-A1 | SMALL MOLECULE ANDROGEN RECEPTOR PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2023-08-17 | — | — | US | disclosed |
| US-20230257365-A1 | SMALL MOLECULE ANDROGEN RECEPTOR PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2023-08-17 | — | — | US | disclosed |
| WO-2022011204-A1 | SMALL MOLECULE ANDROGEN RECEPTOR PROTEIN DEGRADERS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257365-A1 | SMALL MOLECULE ANDROGEN RECEPTOR PROTEIN DEGRADERS | AR, SHBG, CYP19A1 | CRBN 610/4885DDB1 212/4885CSNK1A1 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.