Iodide

Iodide

SCHEMBL2418682

CSC1=NCCCN1.I

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989810 0.98
Hydrochloric Acid SCHEMBL11702150 0.95
Iodide SCHEMBL2889536 0.93 NISCH (0.39)
Iodide SCHEMBL7327222 0.91 NISCH (0.38)
Iodide SCHEMBL7327216 0.91 NISCH (0.38)
SCHEMBL2896154 0.91
Iodomethane SCHEMBL5742685 0.87 NISCH (0.38)
Iodide SCHEMBL315802 0.86
SCHEMBL94280 0.83
Bromide SCHEMBL6976660 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6852731-B2 Antiviral compounds PFIZER (US) 2005-02-08 US claimed
US-20040242884-A1 ANTIVIRAL COMPOUNDS PHARMACIA & UPJOHN COMPANY 2004-12-02 US claimed
US-12582718-B2 Integrin targeting ligands and uses thereof Arrowhead Pharmaceuticals, Inc. (US) 2026-03-24 US disclosed
EP-3784267-B1 INTEGRIN TARGETING LIGANDS AND USES THEREOF ARROWHEAD PHARMACEUTICALS INC (US) 2025-11-12 EP disclosed
US-12006294-B2 Therapeutic compounds REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2024-06-11 US disclosed
US-20210069337-A1 INTEGRIN TARGETING LIGANDS AND USES THEREOF SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT 2021-03-11 US disclosed
EP-3784267-A1 INTEGRIN TARGETING LIGANDS AND USES THEREOF Arrowhead Pharmaceuticals, Inc. (US) 2021-03-03 EP disclosed
US-20190330157-A1 THERAPEUTIC COMPOUNDS REGENTS OF THE UNIVERSITY OF MINNESOTA 2019-10-31 US disclosed
US-8012985-B2 parasiticides, in particularly against Plasmodium and babesia; antimalarial agents CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2011-09-06 US disclosed
US-7125883-B1 Integrin receptor ligands ABBOTT GMBH & CO. KG (DE) 2006-10-24 US disclosed
US-20050176819-A1 Compounds with antiparasitic activity and medicines containing same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. (FR) 2005-08-11 US disclosed
US-4725596-A Pyrimidine derivatives having anti-allergy, anti-inflammatory and immuno suppressant activity SCHERING CORPORATION (US) 1988-02-16 US disclosed
EP-0220282-A1 PYRIMIDINE DERIVATIVES HAVING ANTI-ALLERGY, ANTI-INFLAMMATORY AND IMMUNO SUPPRESSANT ACTIVITY SCHERING CORPORATION (US) 1987-05-06 EP disclosed
US-4642345-A BRONCHODILATOR AGENTS MEAD JOHNSON & COMPANY (US) 1987-02-10 US disclosed
WO-1986006375-A2 PYRIMIDINE DERIVATIVES HAVING ANTI-ALLERGY, ANTI-INFLAMMATORY AND IMMUNO SUPPRESSANT ACTIVITY SCHERING CORPORATION (US) 1986-11-06 WO disclosed
US-4489078-A Diazaheterocyclopurines used as anti-broncho spasmatics and vasodilators MEAD JOHNSON & COMPANY (US) 1984-12-18 US disclosed
US-4404380-A BRONCHODILATORS, MEDIATOR RELEASE INHIBITORS, PHOSPHODIESTERASE INHIBITORS, AND VASODILATORS MEAD JOHNSON & COMPANY (US) 1983-09-13 US disclosed
US-4366156-A Antiallergic methods using diazaheterocyclopurines MEAD JOHNSON & COMPANY (US) 1982-12-28 US disclosed
US-4298734-A PHOSPHODIESTERASE INHIBITORS, BRONCHODILATORS, PERIPHERAL VASODILATORS MEAD JOHNSON & COMPANY (US) 1981-11-03 US disclosed
US-3931152-A ANTITUBERCULAR AMERICAN CYANAMID COMPANY (US) 1976-01-06 US disclosed