SCHEMBL989810

SCHEMBL989810

CSC1=NCCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11702150 0.98
Iodide SCHEMBL2418682 0.98
SCHEMBL2896154 0.93
Iodide SCHEMBL2889536 0.91 NISCH (0.39)
Iodide SCHEMBL7327216 0.89 NISCH (0.38)
Iodide SCHEMBL7327222 0.89 NISCH (0.38)
Iodomethane SCHEMBL5742685 0.89 NISCH (0.38)
SCHEMBL94280 0.85
Bromide SCHEMBL6976660 0.83
Hydrochloric Acid SCHEMBL3171903 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339947-A1 USE OF CASEINOLYTIC PROTEASE P FUNCTION AS A BIOMARKER OF DRUG RESPONSE TO IMIPRIDONE-LIKE AGENTS Madera Therapeutics, LLC 2023-10-26 US disclosed
US-20230339947-A1 USE OF CASEINOLYTIC PROTEASE P FUNCTION AS A BIOMARKER OF DRUG RESPONSE TO IMIPRIDONE-LIKE AGENTS Madera Therapeutics, LLC 2023-10-26 US disclosed
US-11530180-B2 Alpha-5 beta-1 inhibitors THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-12-20 US disclosed
US-11530180-B2 Alpha-5 beta-1 inhibitors THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-12-20 US disclosed
CN-115348861-A Alpha-5 beta-1 inhibitors 加利福尼亚大学董事会 2022-11-15 CN disclosed
EP-4072541-A1 ALPHA-5 BETA-1 INHIBITORS The Regents of the University of California (US) 2022-10-19 EP disclosed
WO-2021119199-A1 ALPHA-5 BETA-1 INHIBITORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-17 WO disclosed
WO-2021119199-A1 ALPHA-5 BETA-1 INHIBITORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-17 WO disclosed
US-20210171455-A1 ALPHA-5 BETA-1 INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-06-10 US disclosed
US-20210171455-A1 ALPHA-5 BETA-1 INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-06-10 US disclosed
US-4558128-A ANTIHISTAMINE, ANTIINFLAMMATORY AGENT SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1985-12-10 US disclosed
US-4489078-A Diazaheterocyclopurines used as anti-broncho spasmatics and vasodilators MEAD JOHNSON & COMPANY (US) 1984-12-18 US disclosed
EP-0109023-A1 Isoquinolinesulfonamide derivatives and process for the preparation thereof Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-05-23 EP disclosed
US-4439435-A PYRIMIDONE OR PYRIMID-THIONE DERIVATIVES, HISTAMINE ANTAGONIST, ANTIINFLAMMATORY SMITH KLINE & FRENCH LABORATORIES LTD. (GB) 1984-03-27 US disclosed
US-4404380-A BRONCHODILATORS, MEDIATOR RELEASE INHIBITORS, PHOSPHODIESTERASE INHIBITORS, AND VASODILATORS MEAD JOHNSON & COMPANY (US) 1983-09-13 US disclosed
US-4366156-A Antiallergic methods using diazaheterocyclopurines MEAD JOHNSON & COMPANY (US) 1982-12-28 US disclosed
US-4305945-A Isoureas and isothioureas SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1981-12-15 US disclosed
US-4298734-A PHOSPHODIESTERASE INHIBITORS, BRONCHODILATORS, PERIPHERAL VASODILATORS MEAD JOHNSON & COMPANY (US) 1981-11-03 US disclosed
EP-0007232-A1 Iso(thio)ureas, processes for their preparation and compositions containing them SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1980-01-23 EP disclosed
US-3969506-A BRONCHODILATOR SANDOZ, INC. (US) 1976-07-13 US disclosed