Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 17/20 | 0.47 |
| ▸ | MMP2 | P08253 | 6/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24187205 | 0.85 | ADAMTS5 (0.65) | ADAMTS5MMP2ADAMTS4ADAM17 | |
| SCHEMBL24187200 | 0.80 | ADAMTS5 (0.59) | ADAMTS5MMP2ADAMTS4ADAM17 | |
| SCHEMBL24187198 | 0.78 | ADAMTS5 (0.65) | ADAMTS5MMP2ADAMTS4ADAM17 | |
| SCHEMBL24187393 | 0.78 | ADAMTS5 (0.65) | ADAMTS5MMP2ADAMTS4ADAM17 | |
| SCHEMBL24187395 | 0.78 | ADAMTS5 (0.65) | ADAMTS5MMP2ADAMTS4ADAM17 | |
| SCHEMBL25948111 | 0.77 | ADAMTS5 (0.70) | ADAMTS5MMP2ADAMTS4ADAM17 | |
| SCHEMBL19996703 | 0.73 | ADAMTS5 (0.74) | ADAMTS5MMP2ADAMTS4ADAM17 | |
| SCHEMBL23745366 | 0.73 | ADAMTS5 (0.46) | ADAMTS5MMP2ADAMTS4ADAM17 | |
| SCHEMBL24187202 | 0.73 | ADAMTS5 (0.60) | ADAMTS5MMP2ADAMTS4ADAM17 | |
| SCHEMBL23745300 | 0.72 | ADAMTS5 (0.49) | ADAMTS5MMP2ADAMTS4ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022007866-A1 | FUSED TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 深圳信立泰药业股份有限公司 | 2022-01-13 | — | — | WO | disclosed |