Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 20/20 | 0.63 |
| ▸ | MMP2 | P08253 | 6/20 | 0.63 |
| ▸ | MMP13 | P45452 | 1/20 | 0.63 |
| ▸ | MMP14 | P50281 | 1/20 | 0.63 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.62 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24187265 | 1.00 | ADAMTS5 (0.63) | ADAMTS5MMP2MMP13MMP14ADAM17 | |
| SCHEMBL24187266 | 1.00 | ADAMTS5 (0.63) | ADAMTS5MMP2MMP13MMP14ADAM17 | |
| SCHEMBL24187242 | 0.94 | ADAMTS5 (0.63) | ADAMTS5MMP2MMP13MMP14ADAM17 | |
| SCHEMBL24187244 | 0.94 | ADAMTS5 (0.63) | ADAMTS5MMP2MMP13MMP14ADAM17 | |
| SCHEMBL24187247 | 0.94 | ADAMTS5 (0.63) | ADAMTS5MMP2MMP13MMP14ADAM17 | |
| SCHEMBL24187238 | 0.94 | ADAMTS5 (0.63) | ADAMTS5MMP2MMP13MMP14ADAM17 | |
| SCHEMBL24187234 | 0.94 | ADAMTS5 (0.63) | ADAMTS5MMP2MMP13MMP14ADAM17 | |
| SCHEMBL24187270 | 0.94 | ADAMTS5 (0.63) | ADAMTS5MMP2MMP13MMP14ADAM17 | |
| SCHEMBL24187277 | 0.90 | ADAMTS5 (0.68) | ADAMTS5MMP2MMP13MMP14ADAM17 | |
| SCHEMBL24187375 | 0.90 | ADAMTS5 (0.63) | ADAMTS5MMP2MMP13MMP14ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115720578-A | Tricyclic derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| WO-2022007866-A1 | FUSED TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 深圳信立泰药业股份有限公司 | 2022-01-13 | — | — | WO | disclosed |