Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 17/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.51 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24187462 | 0.92 | ADAMTS5 (0.55) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 | |
| SCHEMBL24187311 | 0.90 | ADAMTS5 (0.60) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 | |
| SCHEMBL24187520 | 0.89 | ADAMTS5 (0.57) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 | |
| SCHEMBL24187287 | 0.86 | ADAMTS5 (0.58) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 | |
| SCHEMBL24187230 | 0.85 | ADAMTS5 (0.54) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 | |
| SCHEMBL24187392 | 0.83 | ADAMTS5 (0.58) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 | |
| SCHEMBL24187319 | 0.82 | ADAMTS5 (0.55) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 | |
| SCHEMBL24187483 | 0.80 | ADAMTS5 (0.45) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 | |
| SCHEMBL23745408 | 0.79 | ADAMTS5 (0.58) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 | |
| SCHEMBL24187312 | 0.79 | ADAMTS5 (0.56) | ADAMTS5ADAM17ADAMTS4ADAM10MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022007866-A1 | FUSED TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 深圳信立泰药业股份有限公司 | 2022-01-13 | — | — | WO | disclosed |