Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.73 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.73 |
| ▸ | F3 | P13726 | 3/20 | 0.73 |
| ▸ | PNLIP | P16233 | 1/20 | 0.73 |
| ▸ | NOS2 | P35228 | 1/20 | 0.73 |
| ▸ | CES1 | P23141 | 4/20 | 0.63 |
| ▸ | CES2 | O00748 | 2/20 | 0.63 |
| ▸ | RELA | Q04206 | 5/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.63 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.56 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.55 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.55 |
| ▸ | PTPRC | P08575 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24190825 | 0.90 | F3 (0.68) | PTPN1PTPN2F3PNLIPNOS2 | |
| SCHEMBL24190882 | 0.90 | F3 (0.68) | PTPN1PTPN2F3PNLIPNOS2 | |
| SCHEMBL24190746 | 0.86 | HIF1A (0.58) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL18687844 | 0.85 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL18688313 | 0.85 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12337276 | 0.85 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12200334 | 0.85 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL2762433 | 0.85 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL6898284 | 0.85 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12313105 | 0.85 | PTPN2 (1.00) | PTPN1PTPN2F3PNLIPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022007765-A1 | PENTACYCLIC TRITERPENOID GLYCOSIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2022-01-13 | — | — | WO | disclosed |