Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 7/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 7/20 | 1.00 |
| ▸ | F3 | P13726 | 3/20 | 1.00 |
| ▸ | PNLIP | P16233 | 1/20 | 1.00 |
| ▸ | NOS2 | P35228 | 1/20 | 1.00 |
| ▸ | CES1 | P23141 | 4/20 | 0.76 |
| ▸ | CES2 | O00748 | 2/20 | 0.76 |
| ▸ | RELA | Q04206 | 3/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.71 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.71 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.71 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.71 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.71 |
| ▸ | PTPRC | P08575 | 2/20 | 0.71 |
| ▸ | PTPRF | P10586 | 2/20 | 0.71 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.71 |
| ▸ | ACP1 | P24666 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleanonic Acid SCHEMBL18687844 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL18688313 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL2762433 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL16175546 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12200334 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12337276 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL246220 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| Oleanonic Acid SCHEMBL12313105 | 1.00 | PTPN2 (1.00) | PTPN2PTPN1F3PNLIPNOS2 | |
| SCHEMBL17166004 | 0.92 | PTPN1 (0.85) | PTPN2PTPN1F3PNLIPNOS2 | |
| SCHEMBL16152971 | 0.89 | PTPN1 (0.81) | PTPN2PTPN1F3PNLIPNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828326-B2 | Amooranin compounds and analogs thereof and related methods of use | BISHAYEE, Anupam | 2017-11-28 | — | — | US | claimed |
| US-20140357711-A1 | Amooranin Compounds and Analogs Thereof and Related Methods of Use | ENZYME BIO SYSTEMS (US) | 2014-12-04 | — | — | US | claimed |
| WO-2013101719-A2 | AMOORANIN COMPOUNDS AND ANALOGS THEREOF AND RELATED METHODS OF USE | NORTHEAST OHIO MEDICAL UNIVERSITY (US) | 2013-07-04 | — | — | WO | claimed |
| CN-110785181-A | Method for preparing standardized composition of arjuna glucoside from bark of arjuna | 萨米莱布斯有限公司 | 2020-02-11 | — | — | CN | disclosed |
| US-9828326-B2 | Amooranin compounds and analogs thereof and related methods of use | BISHAYEE, Anupam | 2017-11-28 | — | — | US | disclosed |
| US-20140357711-A1 | Amooranin Compounds and Analogs Thereof and Related Methods of Use | ENZYME BIO SYSTEMS (US) | 2014-12-04 | — | — | US | disclosed |
| WO-2013101719-A2 | AMOORANIN COMPOUNDS AND ANALOGS THEREOF AND RELATED METHODS OF USE | NORTHEAST OHIO MEDICAL UNIVERSITY (US) | 2013-07-04 | — | — | WO | disclosed |
| EP-1098626-B1 | METHOD FOR REGULATING HAIR GROWTH | UNIV TEXAS SOUTHWESTERN MED CT (US) | 2004-05-06 | — | — | EP | disclosed |
| US-20030139471-A1 | Compositions which contain triterpenes for regulating hair growth | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2003-07-24 | — | — | US | disclosed |
| US-20030114526-A1 | Administration to a human for hair growth a formulation containing a compound selected from lupane triterpenes and derivatives, derivatives of oleanane triterpenes, derivatives of ursane derivatives or salts and mixtures; antialopecia | PROCTER & GAMBLE TO THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 2003-06-19 | — | — | US | disclosed |
| US-6482857-B1 | Compositions which contain triterpenes for regulating hair growth | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 2002-11-19 | — | — | US | disclosed |
| US-6451777-B1 | Method for regulating hair growth | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 2002-09-17 | — | — | US | disclosed |
| EP-1119338-A2 | COMPOSITIONS WHICH CONTAIN TRITERPENES FOR REGULATING HAIR GROWTH | The University of Texas Southwestern Medical Center (US) | 2001-08-01 | — | — | EP | disclosed |
| EP-1098626-A2 | METHOD FOR REGULATING HAIR GROWTH | UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2001-05-16 | — | — | EP | disclosed |
| US-6124362-A | TOPICAL ADMINISTRATION OF LUPANE TRITERPENES, DERIVATIVES OF LUPANE TRITERPENES, DERIVATIVES OF OLEANANE TRITERPENES, DERIVATIVES OF URSANE TRITERPENES, AND SALTS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| WO-2000003749-A2 | METHOD FOR REGULATING HAIR GROWTH | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2000-01-27 | — | — | WO | disclosed |
| WO-2000003748-A2 | COMPOSITIONS WHICH CONTAIN TRITERPENES FOR REGULATING HAIR GROWTH | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (US) | 2000-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114526-A1 | Administration to a human for hair growth a formulation containing a compound selected from lupane triterpenes and derivatives, derivatives of oleanane triterpenes, derivatives of ursane derivatives or salts and mixtures; antialopecia | LSS, CUTA, NR5A1 | PTPN2 3657/4885PTPN1 3903/4885F3 4272/4885 |
| US-20030139471-A1 | Compositions which contain triterpenes for regulating hair growth | NR5A1, CYP17A1, CYP21A2 | PTPN2 2205/4885PTPN1 2822/4885F3 3977/4885 |
| US-20140357711-A1 | Amooranin Compounds and Analogs Thereof and Related Methods of Use | CYP27A1, OAT, AOX1 | PTPN2 4796/4885PTPN1 4749/4885F3 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.