Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.56 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.54 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | PTPRF | P10586 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24190746 | 0.90 | HIF1A (0.58) | HIF1AEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL24190850 | 0.89 | PTPN1 (0.69) | HIF1AEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL24190889 | 0.89 | PTPN1 (0.69) | HIF1AEGLN2EGLN1EGLN3P4HTM | |
| SCHEMBL24190825 | 0.87 | F3 (0.68) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL24190882 | 0.87 | F3 (0.68) | EGLN2EGLN1EGLN3P4HTMPTPN1 | |
| SCHEMBL24190788 | 0.84 | PTPN1 (0.56) | HIF1APTPN1MEN1KMT2APTPN2 | |
| SCHEMBL25467148 | 0.84 | PTPN1 (0.56) | HIF1APTPN1MEN1KMT2APTPN2 | |
| SCHEMBL24190885 | 0.82 | HIF1A (0.48) | HIF1APTPN1MEN1KMT2APTPN2 | |
| SCHEMBL24190752 | 0.82 | RELA (0.54) | HIF1APTPN1MEN1KMT2APTPN2 | |
| Ursonic Acid SCHEMBL6896631 | 0.81 | PTPN1 (0.72) | HIF1APTPN1MEN1KMT2APTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180445-A1 | PENTACYCLIC TRITERPENOID GLYCOSIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-05-17 | — | — | EP | disclosed |
| WO-2022007765-A1 | PENTACYCLIC TRITERPENOID GLYCOSIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2022-01-13 | — | — | WO | disclosed |