Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 8/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30311310 | 0.90 | DHFR (0.67) | DHFR | |
| SCHEMBL24344753 | 0.90 | DHFR (0.67) | DHFR | |
| SCHEMBL24192603 | 0.90 | DHFR (0.67) | DHFR | |
| SCHEMBL24192552 | 0.90 | DHFR (0.61) | DHFRCA1CA2 | |
| SCHEMBL24192605 | 0.88 | DHFR (0.75) | DHFR | |
| SCHEMBL24193038 | 0.86 | DHFR (0.60) | DHFR | |
| SCHEMBL24343630 | 0.85 | DHFR (0.64) | DHFR | |
| SCHEMBL24344156 | 0.85 | DHFR (0.64) | DHFR | |
| SCHEMBL24192610 | 0.84 | DHFR (0.65) | DHFR | |
| SCHEMBL24344100 | 0.84 | DHFR (0.71) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008419-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2022-01-13 | — | — | WO | disclosed |