Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23166003 | 0.84 | KDM4E (0.46) | HDAC1HDAC6KDM4EL3MBTL1 | |
| SCHEMBL30104774 | 0.84 | KDM4E (0.46) | HDAC1HDAC6KDM4EL3MBTL1 | |
| SCHEMBL23205995 | 0.83 | KMT2A (0.41) | HDAC1HDAC6KAT6A | |
| SCHEMBL24196386 | 0.82 | MALT1 (0.37) | HDAC1HDAC6ACKR3MALT1KAT6A | |
| SCHEMBL31316774 | 0.76 | GAA (0.42) | KAT6APARP1 | |
| SCHEMBL23166193 | 0.76 | BAZ2B (0.36) | ACKR3MALT1NFKB1NFKB2RELA | |
| SCHEMBL15401858 | 0.74 | MAPT (0.54) | MALT1L3MBTL1 | |
| SCHEMBL3833826 | 0.74 | HTT (0.47) | KAT6AKDM4EL3MBTL1 | |
| SCHEMBL23701920 | 0.72 | CYP3A4 (0.38) | HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL18315829 | 0.72 | KMT2A (0.35) | ACKR3KAT6AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | disclosed |