SCHEMBL24196262

SCHEMBL24196262

C=CC(=O)OCCOC(=O)C1CCC(C2CCC(C(=O)Oc3ccccc3)CC2)CC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.55
ELANE P08246 2/20 0.47
POLB P06746 3/20 0.41
KMT2A Q03164 2/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
RAB9A P51151 2/20 0.40
MAPT P10636 2/20 0.40
F2 P00734 1/20 0.39
PKM P14618 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 5/20 0.37
TSHR P16473 3/20 0.37
TP53 P04637 2/20 0.37
HIF1A Q16665 2/20 0.37
HSD17B10 Q99714 1/20 0.37
TEAD1 P28347 1/20 0.37
TEAD3 Q99594 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24609086 0.96 THRB (0.58) THRBELANEPOLBKMT2AHTT
SCHEMBL24196285 0.95 THRB (0.49) THRBELANEPOLBKMT2AHTT
SCHEMBL24196278 0.95 THRB (0.49) THRBELANEPOLBKMT2AHTT
SCHEMBL24992569 0.91 THRB (0.52) THRBELANEPOLBKMT2AHTT
SCHEMBL24196691 0.91 THRB (0.50) THRBELANEPOLBKMT2AHTT
SCHEMBL26023629 0.90 ELANE (0.47) THRBELANEPOLBKMT2AHTT
SCHEMBL24196270 0.89 THRB (0.51) THRBELANEPOLBKMT2AHTT
SCHEMBL24196260 0.89 THRB (0.51) THRBELANEPOLBKMT2AHTT
SCHEMBL24196711 0.89 THRB (0.50) THRBELANEPOLBKMT2AHTT
SCHEMBL22667665 0.89 HTT (0.45) THRBELANEPOLBKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11732191-B2 Compound, polymerizable composition, cured product, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-11732191-B2 Compound, polymerizable composition, cured product, optical film, polarizing plate, and image display device FUJIFILM CORPORATION (JP) 2023-08-22 US disclosed
US-20230037751-A1 OPTICALLY ANISOTROPIC LAYER, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-02-09 US disclosed
US-20220220381-A1 OPTICALLY ANISOTROPIC LAYER, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-07-14 US disclosed
US-20220214484-A1 OPTICALLY ANISOTROPIC LAYER, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-07-07 US disclosed
US-20220010209-A1 COMPOUND, POLYMERIZABLE COMPOSITION, CURED PRODUCT, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2022-01-13 US disclosed