Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.58 |
| ▸ | PI4KA | P42356 | 3/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | AHCY | P23526 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24708227 | 0.94 | YTHDC1 (0.88) | YTHDC1ADORA2AADORA3ADORA1PI4KA | |
| SCHEMBL26255189 | 0.80 | YTHDC1 (0.66) | YTHDC1ADORA2AADORA3ADORA1PI4KA | |
| SCHEMBL24197135 | 0.79 | YTHDC1 (0.64) | YTHDC1ADORA2AADORA3ADORA1PI4KA | |
| SCHEMBL12143425 | 0.78 | ADORA2A (0.65) | YTHDC1ADORA2AADORA3ADORA1PI4KA | |
| SCHEMBL26255179 | 0.78 | YTHDC1 (0.63) | YTHDC1ADORA2AADORA3ADORA1PI4KA | |
| SCHEMBL30679403 | 0.78 | YTHDC1 (0.69) | YTHDC1ADORA3ADORA1PI4KAPI4K2B | |
| SCHEMBL20322942 | 0.78 | YTHDC1 (0.69) | YTHDC1ADORA3ADORA1PI4KAPI4K2B | |
| SCHEMBL9685322 | 0.77 | YTHDC1 (0.60) | YTHDC1ADORA3ADORA1 | |
| SCHEMBL26255190 | 0.77 | YTHDC1 (0.62) | YTHDC1ADORA2AADORA3ADORA1PI4KA | |
| SCHEMBL26255182 | 0.76 | YTHDC1 (0.60) | YTHDC1ADORA2AADORA3ADORA1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011171-A1 | NOVEL COMPOUNDS AND METHODS FOR INCREASING KLOTHO GENE EXPRESSION | KLOTHO THERAPEUTICS, INC. (US) | 2022-01-13 | — | — | WO | disclosed |