Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | PPARG | P37231 | 1/20 | 0.68 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.68 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.68 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22652251 | 0.83 | NPSR1 (0.72) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL14284027 | 0.80 | NPSR1 (0.77) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL18090589 | 0.78 | NPSR1 (0.74) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL2006698 | 0.78 | NPSR1 (0.74) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL25848872 | 0.77 | LMNA (0.72) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL25848977 | 0.75 | LMNA (0.70) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL70027 | 0.74 | NPSR1 (0.67) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL24667372 | 0.73 | NPSR1 (0.66) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL24667362 | 0.71 | LMNA (0.62) | LMNANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL24667471 | 0.71 | LMNA (0.62) | LMNANPSR1PPARGNCOA2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022010880-A1 | KCNT1 INHIBITORS AND METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2022-01-13 | — | — | WO | disclosed |