Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881160 | 0.83 | CYP11B2 (0.50) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL31051044 | 0.81 | DHODH (0.50) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL3876408 | 0.81 | DHODH (0.50) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL18255779 | 0.80 | CYP11B2 (0.47) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL3875252 | 0.80 | CYP11B2 (0.55) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL22230844 | 0.80 | CYP11B2 (0.47) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL12947927 | 0.80 | DHODH (0.48) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL972023 | 0.80 | CYP11B2 (0.47) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL29889660 | 0.79 | MAPT (0.49) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL2489325 | 0.79 | MAPT (0.49) | CYP11B2DHODHMAPTCYP11B1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |