SCHEMBL2419658

SCHEMBL2419658

COC(=O)C(C)=CC(O)CCCO

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.32
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2712987 0.95 ZDHHC7 (0.32) PTPN1
SCHEMBL6849258 0.93 ZDHHC7 (0.34) PTPN1
SCHEMBL2512430 0.93 ZDHHC7 (0.34) PTPN1
SCHEMBL1533657 0.93 ZDHHC7 (0.34) PTPN1
SCHEMBL1155133 0.93 ZDHHC7 (0.34) PTPN1
SCHEMBL25403305 0.93 ZDHHC7 (0.34) PTPN1
SCHEMBL6335679 0.93 ZDHHC7 (0.34) PTPN1
SCHEMBL28186371 0.89 GAA (0.36) TSHR
SCHEMBL8853273 0.89 MIF (0.33) ALDH1A1TSHRTGFBR1
SCHEMBL16162652 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115605529-B Photochromic polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2024-03-26 CN claimed
CN-111919141-B Silicone Hydrogel Contact Lenses 爱尔康公司 2023-11-14 CN claimed
CN-109690360-B Method for producing contact lenses having durable lubricious coatings thereon 爱尔康公司 2023-04-25 CN claimed
CN-115698776-A Insert material with high oxygen permeability coefficient and high refractive index 爱尔康公司 2023-02-03 CN claimed
CN-115605529-A Photochromic polydiorganosiloxane ethylene crosslinkers 爱尔康公司(CH) 2023-01-13 CN claimed
CN-115298573-A High refractive index silicone insert materials for embedded contact lenses 爱尔康公司 2022-11-04 CN claimed
EP-3947490-A1 HIGHLY PROCESSABLE MULTI-STAGE FLEXIBLE ACRYLIC RESINS AND PROCESS FOR MAKING SAME Rohm and Haas Company (US) 2022-02-09 EP claimed
CN-110740855-B Method for producing silicone hydrogel contact lenses 爱尔康公司 2021-10-22 CN claimed
US-20210002469-A1 TOUGH, HEALABLE COMPOSITES DISPLAYING STRESS RELAXATION AT THE RESIN-FILLER INTERFACE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-01-07 US claimed
CN-111919141-A Silicone hydrogel contact lenses 爱尔康公司 2020-11-10 CN claimed
CN-110621483-A Silicone hydrogel contact lenses 爱尔康公司 2019-12-27 CN claimed
WO-2019183140-A1 TOUGH, HEALABLE COMPOSITES DISPLAYING STRESS RELAXATION AT THE RESIN-FILLER INTERFACE THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2019-09-26 WO claimed
CN-107915799-A A kind of new and effective microspheres and preparation method thereof 陈晨特 2018-04-17 CN claimed
CN-106496399-A A kind of organosilicon acrylate and vinyl acetate emulsion and preparation method thereof and obtained redispersible latex powder 宝辰永宇(滁州)新材料科技有限公司 2017-03-15 CN claimed
US-20160039961-A1 MONODISPERSE MICROSPHERES AND METHOD OF PREPARING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2016-02-11 US claimed
US-20160017171-A1 Hybrid Latex Emulsions and Coating Compositions Formed From Hybrid Latex Emulsions AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2016-01-21 US claimed
WO-2010114760-A1 NEW RESIN SYSTEMS FOR DENTAL RESTORATIVE MATERIALS THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2010-10-07 WO claimed
EP-0965619-B1 Low odor, cold curable, (Meth)acylate reactive resin for floor coating, such réactive resin and the process for producing such floorcoating ROEHM GMBH (DE) 2003-07-30 EP claimed
EP-0435536-B1 Adhering an ink jet recording head using photopolymerisable adhesive CANON KK (JP) 1999-07-14 EP claimed
EP-0435536-A2 Adhering an ink jet recording head using photopolymerisable adhesive CANON KABUSHIKI KAISHA (JP) 1991-07-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002469-A1 TOUGH, HEALABLE COMPOSITES DISPLAYING STRESS RELAXATION AT THE RESIN-FILLER INTERFACE CRH, CNKSR1, RAD51 PTPN1 4739/4885ALDH1A1 3679/4885TSHR 3759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.