⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4912204 | 0.84 | — | — | |
| SCHEMBL4911927 | 0.81 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL965233 | 0.76 | — | — | |
| SCHEMBL2411834 | 0.69 | — | — | |
| SCHEMBL10996644 | 0.68 | TSHR (0.31) | — | |
| SCHEMBL16141767 | 0.67 | — | — | |
| SCHEMBL5986940 | 0.67 | — | — | |
| SCHEMBL12734368 | 0.67 | — | — | |
| SCHEMBL1608120 | 0.67 | — | — | |
| SCHEMBL232762 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127413-A1 | Compositions and Methods for Non-Toxic Delivery of Antiprogestins | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2019-05-02 | — | — | US | claimed |
| EP-2550288-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | Repros Therapeutics Inc. (US) | 2013-01-30 | — | — | EP | claimed |
| US-20130018027-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | REPROS THERAPEUTICS INC. (US) | 2013-01-17 | — | — | US | claimed |
| WO-2011119194-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | REPROS THERAPEUTICS INC. (US) | 2011-09-29 | — | — | WO | claimed |
| EP-3865502-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF CDB-2914 | Allergan Pharmaceuticals International Limited (IE) | 2021-08-18 | — | — | EP | disclosed |
| US-20190127413-A1 | Compositions and Methods for Non-Toxic Delivery of Antiprogestins | ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) | 2019-05-02 | — | — | US | disclosed |
| US-20150203526-A1 | NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE- DEPENDENT CONDITIONS | REPROS THERAPEUTICS INC. (US) | 2015-07-23 | — | — | US | disclosed |
| EP-2655394-A1 | NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE-DEPENDENT CONDITIONS | Repros Therapeutics Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| US-20130274234-A1 | NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE- DEPENDENT CONDITIONS | REPROS THERAPEUTICS INC. (US) | 2013-10-17 | — | — | US | disclosed |
| EP-2550288-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | Repros Therapeutics Inc. (US) | 2013-01-30 | — | — | EP | disclosed |
| US-20130018027-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | REPROS THERAPEUTICS INC. (US) | 2013-01-17 | — | — | US | disclosed |
| WO-2012087389-A1 | NOVEL 19-NOR-STEROIDS AND THEIR USE FOR TREATING PROGESTERONE-DEPENDENT CONDITIONS | REPROS THERAPEUTICS INC. (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2011119194-A1 | COMPOSITIONS AND METHODS FOR NON-TOXIC DELIVERY OF ANTIPROGESTINS | REPROS THERAPEUTICS INC. (US) | 2011-09-29 | — | — | WO | disclosed |
| US-20080200475-A1 | 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors | PFIZER INC. | 2008-08-21 | — | — | US | disclosed |
| EP-1866317-A1 | 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006103555-A1 | 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| US-3969392-A | PARASITICIDE, BACTERICIDE, ANTIINFLAMMATORY, SURFACTANT | E. R. SQUIBB & SONS, INC. (US) | 1976-07-13 | — | — | US | disclosed |
| US-3935230-A | α, α, α, α', α', α'-Hexafluorodi-m-tolylamine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |