Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196899 | 0.81 | TAAR1 (0.46) | TAAR1IDO1AGXTCARM1PRMT6 | |
| SCHEMBL24196881 | 0.80 | CYP1A2 (0.45) | CYP1A2CYP2D6CYP2C19TAAR1L3MBTL1 | |
| SCHEMBL21928925 | 0.74 | TAAR1 (0.47) | CYP1A2CYP2D6CYP2C19TAAR1IDO1 | |
| SCHEMBL26622163 | 0.74 | TAAR1 (0.47) | CYP1A2CYP2D6CYP2C19TAAR1IDO1 | |
| SCHEMBL3565658 | 0.74 | TAAR1 (0.50) | CYP1A2CYP2D6CYP2C19TAAR1IDO1 | |
| SCHEMBL30837419 | 0.74 | TAAR1 (0.50) | CYP1A2CYP2D6CYP2C19TAAR1IDO1 | |
| SCHEMBL24196032 | 0.71 | CHRM2 (0.39) | L3MBTL1IDO1NPC1RAB9AALOX15 | |
| SCHEMBL6183546 | 0.71 | CYP1A2 (0.76) | CYP1A2CYP2D6CYP2C19TAAR1L3MBTL1 | |
| SCHEMBL552961 | 0.70 | TAAR1 (0.66) | CYP1A2CYP2D6CYP2C19TAAR1L3MBTL1 | |
| SCHEMBL13331747 | 0.69 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C19TAAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |