Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24196885 | 0.81 | CYP1A2 (0.47) | TAAR1IDO1AGXTCARM1PRMT6 | |
| SCHEMBL10381187 | 0.74 | PNMT (0.50) | TAAR1CHRM2PNMTCYP3A4IDO1 | |
| SCHEMBL30837416 | 0.74 | PNMT (0.54) | TAAR1CHRM2PNMTCYP3A4IDO1 | |
| SCHEMBL3564528 | 0.74 | PNMT (0.54) | TAAR1CHRM2PNMTCYP3A4IDO1 | |
| SCHEMBL7810238 | 0.72 | PNMT (0.52) | TAAR1CHRM2PNMTCYP3A4IDO1 | |
| SCHEMBL21674322 | 0.71 | CHRM2 (0.71) | TAAR1CHRM2PNMTCYP3A4 | |
| SCHEMBL24196032 | 0.71 | CHRM2 (0.39) | CHRM2IDO1 | |
| SCHEMBL24196881 | 0.70 | CYP1A2 (0.45) | TAAR1 | |
| Hydrochloric Acid SCHEMBL31169761 | 0.70 | CHRM2 (0.69) | TAAR1CHRM2PNMTCYP3A4 | |
| SCHEMBL91272 | 0.68 | TAAR1 (0.63) | TAAR1CHRM2PNMTCYP3A4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008475-A1 | INDOLE DERIVATIVES AND USES THEREOF FOR TREATING A CANCER | UNIVERSITE CLAUDE BERNARD LYON 1 (FR) | 2022-01-13 | — | — | WO | disclosed |