Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 2/20 | 0.33 |
| ▸ | HINT1 | P49773 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26347601 | 1.00 | TAS1R3 (0.44) | TAS1R3TAS1R1KDM4EALDH1A1MEN1 | |
| SCHEMBL24181917 | 0.87 | KDM4E (0.53) | TAS1R3TAS1R1KDM4EALDH1A1MEN1 | |
| SCHEMBL3316465 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1KDM4EIMPDH2IMPDH1 | |
| SCHEMBL3316463 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1KDM4EIMPDH2IMPDH1 | |
| SCHEMBL24181916 | 0.87 | KDM4E (0.47) | TAS1R3TAS1R1KDM4EALDH1A1MEN1 | |
| SCHEMBL26347593 | 0.87 | KDM4E (0.47) | TAS1R3TAS1R1KDM4EALDH1A1MEN1 | |
| SCHEMBL3317478 | 0.84 | TAS1R3 (0.45) | TAS1R3TAS1R1KDM4EALDH1A1MEN1 | |
| SCHEMBL3317477 | 0.84 | TAS1R3 (0.45) | TAS1R3TAS1R1KDM4EALDH1A1MEN1 | |
| SCHEMBL29884003 | 0.83 | KDM4E (0.46) | TAS1R3TAS1R1KDM4EALDH1A1MEN1 | |
| SCHEMBL24181915 | 0.82 | KDM4E (0.56) | TAS1R3TAS1R1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3936514-B1 | 3'3' CYCLIC DINUCLEOTIDES WITH AN ALKENYLENE | INST OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR V V I (CZ) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022007986-A1 | 3'3' CYCLIC DINUCLEOTIDES WITH AN ALKENYLENE | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR, V. V. I. (CZ) | 2022-01-13 | — | — | WO | disclosed |