Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 4/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24197548 | 0.87 | AGER (0.41) | HDAC4MEF2DNOS1VNN1LRRK2 | |
| SCHEMBL24197563 | 0.81 | HDAC4 (0.53) | HDAC4MEF2DNOS1CYP19A1FFAR1 | |
| SCHEMBL24197418 | 0.79 | POLB (0.42) | FFAR1FFAR4HDAC8HDAC6PARP1 | |
| SCHEMBL24197345 | 0.76 | AGER (0.54) | CYP19A1FFAR1FFAR4HDAC8HDAC6 | |
| SCHEMBL30416299 | 0.76 | MGAM (0.52) | — | |
| SCHEMBL24197553 | 0.76 | MGAM (0.52) | — | |
| SCHEMBL24197352 | 0.75 | CYP19A1 (0.43) | CYP19A1FFAR1FFAR4VNN1HDAC8 | |
| SCHEMBL8055849 | 0.73 | MEN1 (0.37) | LMNA | |
| SCHEMBL24197552 | 0.73 | HDAC4 (0.40) | HDAC4MEF2DNOS1CYP19A1LRRK2 | |
| SCHEMBL9454973 | 0.71 | HDAC8 (0.57) | HDAC4MEF2DFFAR1FFAR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011211-A1 | DEOXYNOJIRIMYCIN DERIVATIVES AS GLUCOSIDASE INHIBITORS | EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. (US) | 2022-01-13 | — | — | WO | disclosed |