Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198777 | 0.83 | TDP1 (0.42) | ALDH1A1HTTKDM4EL3MBTL1CYP3A4 | |
| SCHEMBL24198699 | 0.80 | TDP1 (0.40) | SMN1; SMN2ALDH1A1HTTKDM4EL3MBTL1 | |
| SCHEMBL10001158 | 0.79 | EGLN2 (0.47) | ALDH1A1KDM4EL3MBTL1CYP3A4MAPT | |
| SCHEMBL365395 | 0.79 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1HTTKDM4EL3MBTL1 | |
| SCHEMBL4445637 | 0.78 | GRM4 (0.43) | ALDH1A1KDM4EL3MBTL1CYP3A4MAPT | |
| SCHEMBL15113253 | 0.78 | MAPT (0.40) | ALDH1A1HTTKDM4EL3MBTL1CYP3A4 | |
| SCHEMBL2414354 | 0.77 | POLB (0.44) | ALDH1A1L3MBTL1LMNATRPV1TRPA1 | |
| SCHEMBL6415070 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HTTTSHRTRPV1 | |
| SCHEMBL17448840 | 0.76 | KDM4E (0.39) | ALDH1A1KDM4EL3MBTL1CYP3A4MAPT | |
| SCHEMBL13379449 | 0.76 | KDM4E (0.46) | ALDH1A1KDM4EL3MBTL1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225505-B2 | Antimicrobial polymyxin derivative compounds | MONASH UNIVERSITY (AU) | 2022-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11225505-B2 | Antimicrobial polymyxin derivative compounds | VIP, PNKP, PEPD | SMN1; SMN2 4738/4885ALDH1A1 4859/4885HTT 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.