Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | FABP7 | O15540 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633962 | 0.90 | ITGB3 (0.38) | PTPN1TRPM8PPARGPPARDPPARA | |
| SCHEMBL29633950 | 0.90 | PPARG (0.33) | PTPN1TRPM8PPARGPPARDPPARA | |
| SCHEMBL29633681 | 0.90 | PPARG (0.33) | PTPN1TRPM8PPARGPPARDPPARA | |
| SCHEMBL22454862 | 0.90 | PPARG (0.33) | PTPN1TRPM8PPARGPPARDPPARA | |
| SCHEMBL29633877 | 0.83 | EPHX2 (0.34) | PTPN1TRPM8PPARGPPARDPPARA | |
| SCHEMBL29633839 | 0.81 | EPHX2 (0.33) | PTPN1TRPM8EPHX2KMT2AFFAR1 | |
| SCHEMBL29633837 | 0.80 | FABP5 (0.38) | PTPN1PPARGPPARAEPHX2XIAP | |
| SCHEMBL29633668 | 0.80 | FABP7 (0.35) | PTPN1PPARGPPARAEPHX2XIAP | |
| SCHEMBL24633858 | 0.80 | CYP2D6 (0.38) | PTPN1PPARGPPARAEPHX2CYP2D6 | |
| SCHEMBL30055883 | 0.80 | CYP2D6 (0.38) | PTPN1PPARGPPARAEPHX2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939962-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-01-19 | — | — | EP | disclosed |