Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 11/20 | 0.79 |
| ▸ | CTSL | P07711 | 10/20 | 0.79 |
| ▸ | CTSF | Q9UBX1 | 8/20 | 0.79 |
| ▸ | CTSK | P43235 | 13/20 | 0.68 |
| ▸ | CTSS | P25774 | 4/20 | 0.64 |
| ▸ | CTSV | O60911 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22733952 | 1.00 | CTSB (0.79) | CTSBCTSLCTSFCTSKCTSS | |
| SCHEMBL22733949 | 1.00 | CTSB (0.79) | CTSBCTSLCTSFCTSKCTSS | |
| SCHEMBL22733950 | 1.00 | CTSB (0.79) | CTSBCTSLCTSFCTSKCTSS | |
| SCHEMBL22733935 | 0.88 | CTSB (1.00) | CTSBCTSLCTSFCTSKCTSS | |
| SCHEMBL22733995 | 0.88 | CTSB (0.81) | CTSBCTSLCTSFCTSKCTSS | |
| SCHEMBL22733992 | 0.88 | CTSB (0.81) | CTSBCTSLCTSFCTSKCTSS | |
| SCHEMBL22733994 | 0.88 | CTSB (0.81) | CTSBCTSLCTSFCTSKCTSS | |
| SCHEMBL22733937 | 0.88 | CTSB (1.00) | CTSBCTSLCTSFCTSKCTSS | |
| SCHEMBL2156015 | 0.88 | CTSB (1.00) | CTSBCTSLCTSFCTSKCTSS | |
| SCHEMBL3757063 | 0.84 | CTSB (0.75) | CTSBCTSLCTSFCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720840-B1 | CATHEPSIN INHIBITORS | ACADEMISCH ZIEKENHUIS LEIDEN (NL) | 2022-01-19 | — | — | EP | disclosed |