Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 8/20 | 0.54 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694491 | 0.89 | GLS (0.56) | GLSBRD4KDM4ACREBBPIDO1 | |
| SCHEMBL7865700 | 0.83 | GLS (0.58) | GLSBRD4KDM4ACREBBPIDO1 | |
| SCHEMBL16181822 | 0.83 | GLS (0.55) | GLSBRD4KDM4ACREBBPIDO1 | |
| SCHEMBL1165088 | 0.83 | GLS (0.55) | GLSBRD4KDM4ACREBBPIDO1 | |
| SCHEMBL13981921 | 0.83 | GLS (0.55) | GLSBRD4KDM4ACREBBPIDO1 | |
| SCHEMBL30069429 | 0.83 | GLS (0.55) | GLSBRD4KDM4ACREBBPIDO1 | |
| SCHEMBL8342682 | 0.83 | GLS (0.55) | GLSBRD4KDM4ACREBBPNAMPT | |
| SCHEMBL10208317 | 0.82 | GLS (0.57) | GLSBRD4KDM4ACREBBPIDO1 | |
| SCHEMBL3307235 | 0.82 | GLS (0.52) | GLSBRD4KDM4ACREBBPIDO1 | |
| SCHEMBL7015412 | 0.82 | GLS (0.52) | GLSBRD4KDM4ACREBBPIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |