Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713938 | 0.98 | OPRD1 (0.52) | OPRD1SPHK2SPHK1 | |
| SCHEMBL6335780 | 0.98 | OPRD1 (0.52) | OPRD1SPHK2SPHK1 | |
| SCHEMBL4725155 | 0.93 | SPHK2 (0.51) | OPRD1SPHK2SPHK1 | |
| SCHEMBL2446144 | 0.93 | SPHK2 (0.51) | OPRD1SPHK2SPHK1 | |
| SCHEMBL9550064 | 0.93 | SPHK2 (0.51) | OPRD1SPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL8547793 | 0.92 | SPHK2 (0.50) | OPRD1SPHK2SPHK1 | |
| Hydrochloric Acid SCHEMBL8541840 | 0.92 | SPHK2 (0.50) | OPRD1SPHK2SPHK1 | |
| SCHEMBL3665470 | 0.86 | GBA1 (0.47) | SIGMAR1 | |
| SCHEMBL4489433 | 0.86 | MEN1 (0.51) | OPRD1SIGMAR1SPHK2SPHK1 | |
| SCHEMBL11470279 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939954-A1 | METHOD FOR INTRODUCING DEUTERATED LOWER ALKYL INTO AMINE MOIETY OF COMPOUND CONTAINING SECONDARY AMINE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2022-01-19 | — | — | EP | disclosed |