Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 15/20 | 0.45 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21439514 | 0.91 | CFD (0.57) | CFDF11TPSB2SUCNR1 | |
| SCHEMBL21439754 | 0.87 | CFD (0.49) | CFDF11TPSB2SUCNR1HDAC1 | |
| SCHEMBL29095034 | 0.83 | CFD (0.39) | CFDF11TPSB2SUCNR1HDAC1 | |
| SCHEMBL21439598 | 0.76 | CFD (0.58) | CFDF11TPSB2SUCNR1 | |
| SCHEMBL23616918 | 0.75 | CFD (0.50) | CFDF11TPSB2SUCNR1AVPR1B | |
| SCHEMBL21438093 | 0.73 | CFD (0.57) | CFDF11TPSB2SUCNR1 | |
| SCHEMBL21439724 | 0.73 | CFD (0.51) | CFDF11TPSB2SUCNR1 | |
| SCHEMBL21439091 | 0.72 | CFD (0.57) | CFDF11TPSB2 | |
| SCHEMBL21438700 | 0.70 | CFD (0.51) | CFDF11TPSB2SUCNR1AVPR1B | |
| SCHEMBL23616917 | 0.70 | CFD (0.47) | CFDF11TPSB2SUCNR1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |