Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22623893 | 0.82 | HDAC1 (0.44) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL12015723 | 0.74 | PIK3CD (0.50) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL8039385 | 0.74 | KMT2A (0.51) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL12169472 | 0.74 | PIK3CD (0.50) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL10517702 | 0.74 | KMT2A (0.51) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL9424540 | 0.74 | PIK3CD (0.50) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL22330321 | 0.74 | FKBP1A (0.49) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL15374439 | 0.73 | MEN1 (0.65) | KMT2AFKBP1AALDH1A1 | |
| SCHEMBL7779878 | 0.72 | HDAC1 (0.46) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL7779876 | 0.72 | HDAC1 (0.46) | POLBCYP2D6CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939971-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | Synchronicity Pharma, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |