Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 14/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201254 | 0.93 | EPHX2 (0.37) | EPHX2HTT | |
| SCHEMBL24201080 | 0.93 | EPHX2 (0.37) | EPHX2HTT | |
| SCHEMBL22186528 | 0.79 | ALDH1A1 (0.50) | EPHX2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL24201267 | 0.77 | ALOX5AP (0.31) | — | |
| SCHEMBL22186531 | 0.73 | ALDH1A1 (0.43) | EPHX2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL22186527 | 0.73 | ALDH1A1 (0.43) | EPHX2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL22186530 | 0.73 | ALDH1A1 (0.43) | EPHX2HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL24201079 | 0.72 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL24201097 | 0.72 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL24201347 | 0.72 | MEN1 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3618833-B1 | TRIPARTITE ANDROGEN RECEPTOR ELIMINATORS, METHODS AND USES THEREOF | SPG THERAPEUTICS INC (US) | 2022-01-19 | — | — | EP | disclosed |