Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12981321 | 0.85 | MEN1 (0.38) | TSHRGLP1RMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23446432 | 0.84 | TSHR (0.35) | TSHRGLP1RMEN1KMT2ARECQL | |
| SCHEMBL22675545 | 0.84 | GLP1R (0.47) | TSHRGLP1RMEN1KMT2A | |
| SCHEMBL24253207 | 0.84 | TSHR (0.44) | TSHRGLP1RMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20993448 | 0.84 | GLP1R (0.37) | TSHRGLP1RMEN1KMT2ACA12 | |
| SCHEMBL16418488 | 0.82 | MEN1 (0.36) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19239046 | 0.82 | MEN1 (0.36) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24193595 | 0.81 | MEN1 (0.37) | TSHRGLP1RMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21087027 | 0.81 | GLP1R (0.39) | TSHRGLP1RMEN1KMT2ACA12 | |
| SCHEMBL19017546 | 0.81 | GLP1R (0.53) | GLP1RFAAHCASP2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939591-A1 | QUINAZOLINE AND INDOLE COMPOUNDS TO TREAT MEDICAL DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |