Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 5/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 5/20 | 0.46 |
| ▸ | AHCY | P23526 | 2/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 5/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697042 | 0.94 | BCHE (0.53) | BCHEAHCYTP53CYP2C9NFKB1 | |
| SCHEMBL9813105 | 0.81 | AHCY (0.57) | BCHEAHCYTP53CYP2C9NFKB1 | |
| SCHEMBL17804408 | 0.81 | BCHE (0.53) | BCHEAHCYTP53CYP2C9NFKB1 | |
| SCHEMBL7070026 | 0.80 | BCHE (0.53) | BCHEAHCYTP53CYP2C9NFKB1 | |
| SCHEMBL10427715 | 0.79 | BCHE (0.55) | BCHEAHCYTP53CYP2C9NFKB1 | |
| SCHEMBL24181819 | 0.79 | ADA (0.54) | BCHEAHCYTP53CYP2C9NFKB1 | |
| SCHEMBL22458248 | 0.79 | ADORA1 (0.65) | AHCYMAPK1MEN1ALDH1A1PI4KA | |
| SCHEMBL22524135 | 0.78 | BCHE (0.57) | BCHEAHCYTP53CYP2C9NFKB1 | |
| SCHEMBL23516968 | 0.78 | BCHE (0.57) | BCHEAHCYTP53CYP2C9NFKB1 | |
| SCHEMBL20624631 | 0.78 | BCHE (0.57) | BCHEAHCYTP53CYP2C9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939988-A1 | PHARMACEUTICAL COMPOSITION COMPRISING NOVEL AZOLOPYRIMIDINE HETEROCYCLIC COMPOUND AS ACTIVE INGREDIENT | Korea Research Institute of Chemical Technology (KR) | 2022-01-19 | — | — | EP | disclosed |