Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 14/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201396 | 0.91 | SLC9A3 (0.55) | SLC9A3 | |
| SCHEMBL24201327 | 0.90 | SLC9A3 (0.53) | SLC9A3 | |
| SCHEMBL19593613 | 0.87 | SLC9A3 (0.60) | SLC9A3 | |
| SCHEMBL17991934 | 0.86 | SLC9A3 (0.57) | SLC9A3 | |
| SCHEMBL13276190 | 0.83 | SLC9A3 (0.72) | SLC9A3 | |
| SCHEMBL2572075 | 0.83 | SLC9A3 (0.72) | SLC9A3 | |
| SCHEMBL20404549 | 0.82 | SLC9A3 (0.55) | SLC9A3 | |
| SCHEMBL23469886 | 0.82 | SLC9A3 (0.50) | SLC9A3 | |
| SCHEMBL19593915 | 0.82 | SLC9A3 (0.55) | SLC9A3 | |
| SCHEMBL19593451 | 0.81 | SLC9A3 (0.62) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939964-A1 | COMBINATIONS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS | Ardelyx, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |