Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 14/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19593613 | 0.87 | SLC9A3 (0.60) | SLC9A3 | |
| SCHEMBL24201396 | 0.86 | SLC9A3 (0.55) | SLC9A3 | |
| SCHEMBL24201394 | 0.86 | SLC9A3 (0.54) | SLC9A3 | |
| SCHEMBL23469959 | 0.85 | SLC9A3 (0.51) | SLC9A3 | |
| SCHEMBL16883963 | 0.85 | SLC9A3 (0.60) | SLC9A3 | |
| SCHEMBL24201327 | 0.85 | SLC9A3 (0.53) | SLC9A3 | |
| SCHEMBL20953588 | 0.83 | SLC9A3 (0.56) | SLC9A3 | |
| SCHEMBL19593354 | 0.83 | SLC9A3 (0.52) | SLC9A3 | |
| SCHEMBL19593451 | 0.83 | SLC9A3 (0.62) | SLC9A3 | |
| SCHEMBL23469997 | 0.83 | SLC9A3 (0.52) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9408840-B2 | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorder | ARDELYX, INC. (US) | 2016-08-09 | — | — | US | disclosed |