Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | ADH1B | P00325 | 3/20 | 0.42 |
| ▸ | ADH1A | P07327 | 3/20 | 0.42 |
| ▸ | ADH7 | P40394 | 3/20 | 0.42 |
| ▸ | ADH1C | P00326 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18136229 | 0.84 | CA14 (0.54) | CA14EPHX1HDAC1HDAC2HDAC3 | |
| SCHEMBL18599054 | 0.82 | CA14 (0.54) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL14877951 | 0.81 | CA14 (0.58) | CA14EPHX1CA12CA1CA7 | |
| SCHEMBL14877954 | 0.81 | CA14 (0.58) | CA14EPHX1CA12CA1CA7 | |
| SCHEMBL18163279 | 0.81 | CA14 (0.53) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL26616523 | 0.81 | CA14 (0.53) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL8285770 | 0.81 | CA14 (0.51) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL2608081 | 0.80 | CA14 (0.49) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL17083337 | 0.80 | CA14 (0.60) | CA14HDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL12326931 | 0.80 | CA14 (0.41) | CA14HDAC1HDAC2HDAC3NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939981-A1 | FUSED THIAZOLOPYRIMIDINE DERIVATIVES AS MNKS INHIBITORS | LifeArc (GB) | 2022-01-19 | — | — | EP | disclosed |