Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21061651 | 0.90 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL29500851 | 0.90 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL16094929 | 0.88 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL30435857 | 0.83 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL9101688 | 0.81 | MEN1 (0.52) | ALDH1A1SMN1; SMN2NPC1RAB9APTPN1 | |
| SCHEMBL3750320 | 0.81 | HSD17B10 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL19783798 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL29848981 | 0.79 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL2435599 | 0.77 | PDGFRB (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL1289600 | 0.76 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017513-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | SHANGHAI JEMINCARE PHARMACEUTICALS CO., LTD (CN) | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017513-A1 | AROMATIC RING DERIVATIVE AS IMMUNOREGULATION AND PREPARATION METHOD AND APPLICATION OF AROMATIC RING DERIVATIVE | S1PR1, S1PR2, S1PR3 | ALDH1A1 1752/4885SMN1; SMN2 4722/4885NPC1 532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.