Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.31 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286781 | 1.00 | TSHR (0.46) | TSHRHTR2CMAOBCYP2A6PNMT | |
| SCHEMBL4166749 | 0.86 | TSHR (0.53) | TSHRHTR2CMAOBCYP2A6PNMT | |
| SCHEMBL2588517 | 0.85 | TSHR (0.55) | TSHRHTR2CMAOBCYP2A6PNMT | |
| SCHEMBL4781186 | 0.83 | TSHR (0.59) | TSHRHTR2CMAOBCYP2A6PNMT | |
| SCHEMBL1623564 | 0.80 | — | — | |
| SCHEMBL157430 | 0.80 | — | — | |
| SCHEMBL379730 | 0.72 | — | — | |
| SCHEMBL141176 | 0.72 | — | — | |
| SCHEMBL8806125 | 0.70 | PARP1 (0.34) | HTR2CDRD2DRD3 | |
| SCHEMBL8807519 | 0.70 | HTR1D (0.35) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2396 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | claimed |
| US-20230348387-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2023-11-02 | — | — | US | claimed |
| US-20230174486-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2023-06-08 | — | — | US | claimed |
| CN-115867534-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2023-03-28 | — | — | CN | claimed |
| WO-2023042177-A1 | ENANTIOMERS OF 5-((7-CHLOROISOQUINOLIN-1-YL)AMINO)-N-(6-METHOXY-1,2,3,4-TETRAHYDRONAPHTHALEN-2-YL)PICOLINAMIDE | GT GAIN THERAPEUTICS SA (CH) | 2023-03-23 | — | — | WO | claimed |
| EP-4146624-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | Alectos Therapeutics Inc. (CA) | 2023-03-15 | — | — | EP | claimed |
| EP-4146623-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | Alectos Therapeutics Inc. (CA) | 2023-03-15 | — | — | EP | claimed |
| CN-115803025-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2023-03-14 | — | — | CN | claimed |
| US-20230053746-A1 | IL-17 LIGANDS AND USES THEREOF | DICE MOLECULES SV, INC. | 2023-02-23 | — | — | US | claimed |
| US-20220280527-A1 | TRACE AMINE ASSOCIATED RECEPTOR 1 AGONISTS AND PARTIAL AGONISTS FOR PAIN TREATMENT | PURDUE PHARMA L.P. (US) | 2022-09-08 | — | — | US | claimed |
| EP-0512352-A2 | Substituted carboxylic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-11-11 | — | — | EP | claimed |
| US-4987130-A | ANTIARRHYTHMIA AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-01-22 | — | — | US | claimed |
| US-4882339-A | ANTIINFLAMMATORY, ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1989-11-21 | — | — | US | claimed |
| EP-0335375-A2 | Antihyperlipidemic and antiatherosclerotic compounds and compositions | WARNER-LAMBERT COMPANY (US) | 1989-10-04 | — | — | EP | claimed |
| US-4833169-A | MEMORY ACTIVATORS | CIBA-GEIGY CORPORATION (US) | 1989-05-23 | — | — | US | claimed |
| EP-0213080-A2 | Hydrogenated pyridine derivatives | CIBA-GEIGY AG (CH) | 1987-03-04 | — | — | EP | claimed |
| EP-0068144-A1 | 1,1-Diphenyl-2-triazolyl-ethanes, their preparation and their application as fungicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | claimed |
| US-4136185-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, ADRENOLYTICS, ANTIPHLOGISTICS, ANALGESICS, ANTIHISTAMINES, ANTICHOLESTEROL AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1979-01-23 | — | — | US | claimed |
| US-3935218-A | Imidazolinyl phenyl carbonyl compounds acid addition salts and related compounds | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-27 | — | — | US | claimed |
| US-3931218-A | HYPOGLYCEMIC ANTIRESERPINE, ANTIULCER, OGENIC, ANTIARRHYTHMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-06 | — | — | US | claimed |