Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.31 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24203 | 1.00 | TSHR (0.46) | TSHRHTR2CMAOBCYP2A6PNMT | |
| SCHEMBL4166749 | 0.86 | TSHR (0.53) | TSHRHTR2CMAOBCYP2A6PNMT | |
| SCHEMBL2588517 | 0.85 | TSHR (0.55) | TSHRHTR2CMAOBCYP2A6PNMT | |
| SCHEMBL4781186 | 0.83 | TSHR (0.59) | TSHRHTR2CMAOBCYP2A6PNMT | |
| SCHEMBL1623564 | 0.80 | — | — | |
| SCHEMBL157430 | 0.80 | — | — | |
| SCHEMBL379730 | 0.72 | — | — | |
| SCHEMBL141176 | 0.72 | — | — | |
| SCHEMBL8806125 | 0.70 | PARP1 (0.34) | HTR2CDRD2DRD3 | |
| SCHEMBL8807519 | 0.70 | HTR1D (0.35) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343697-B2 | Electrophotographic photoconductor and image forming apparatus provided with the same | SHARP KABUSHIKI KAISHA (JP) | 2013-01-01 | — | — | US | claimed |
| US-20090257777-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2009-10-15 | — | — | US | claimed |
| US-9127098-B2 | O-imino-iso-urea compounds and polymerizable compositions thereof | BASF SE (DE) | 2015-09-08 | — | — | US | disclosed |
| EP-2427428-B1 | O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF | BASF SE (DE) | 2015-08-19 | — | — | EP | disclosed |
| US-20140113987-A1 | O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF | BASF SE (DE) | 2014-04-24 | — | — | US | disclosed |
| US-8664288-B2 | O-imino-iso-urea compounds and polymerizable compositions thereof | BASF SE (DE) | 2014-03-04 | — | — | US | disclosed |
| US-8343697-B2 | Electrophotographic photoconductor and image forming apparatus provided with the same | SHARP KABUSHIKI KAISHA (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20120108696-A1 | O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| EP-2427428-A1 | O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128062-A1 | O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF | BASF SE (DE) | 2010-11-11 | — | — | WO | disclosed |
| US-20090257777-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2009-10-15 | — | — | US | disclosed |
| WO-2008005670-A2 | ONE-POT CONDENSATION REDUCTION METHODS FOR PREPARING SUBSTITUTED ALLYLIC ALCOHOLS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-10 | — | — | WO | disclosed |
| US-20080009628-A1 | One-Pot Condensation-Reduction Methods for Preparing Substituted Allylic Alcohols | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-01-10 | — | — | US | disclosed |
| US-20060004028-A1 | Novel PARP inhibitor | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1582520-A1 | NOVEL PARP INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2005-10-05 | — | — | EP | disclosed |
| US-5076831-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |
| EP-0430004-A2 | 1,8-Naphthalimides as antidotes | BASF Aktiengesellschaft (DE) | 1991-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004028-A1 | Novel PARP inhibitor | PARP1, PARP2, PARP11 | TSHR 4765/4885HTR2C 3206/4885MAOB 2568/4885 |
| US-20120108696-A1 | O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF | CCNC, CCNO, CCNI | TSHR 2345/4885HTR2C 1650/4885MAOB 967/4885 |
| US-20080009628-A1 | One-Pot Condensation-Reduction Methods for Preparing Substituted Allylic Alcohols | ADH1A, ADH1C, TALDO1 | TSHR 3545/4885HTR2C 3391/4885MAOB 2746/4885 |
| US-20140113987-A1 | O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF | CCNC, CPS1, ODC1 | TSHR 2083/4885HTR2C 1970/4885MAOB 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.