Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.62 |
| ▸ | RAB9A | P51151 | 12/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.57 |
| ▸ | HPGD | P15428 | 10/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24205753 | 1.00 | NPC1 (0.62) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL24205727 | 0.92 | RAB9A (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL24205685 | 0.92 | RAB9A (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL19601392 | 0.92 | NPC1 (0.72) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL10047620 | 0.90 | NPC1 (0.56) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL12249738 | 0.89 | NPC1 (0.56) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL10315409 | 0.89 | NPC1 (0.55) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL10315173 | 0.88 | NPC1 (0.54) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL22103755 | 0.87 | NPC1 (0.67) | NPC1RAB9AKDM4ESMN1; SMN2HPGD | |
| SCHEMBL22791712 | 0.86 | NPC1 (0.55) | NPC1RAB9AKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017503-A1 | TRIBENZAZOLE AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | LAPTO CO., LTD. (KR) | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017503-A1 | TRIBENZAZOLE AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | CYP2E1, CYP1B1, ODC1 | NPC1 4030/4885RAB9A 2949/4885KDM4E 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.