Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.55 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.53 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.48 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31294962 | 1.00 | KDM4E (0.56) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL31294933 | 1.00 | KDM4E (0.56) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL31294961 | 1.00 | KDM4E (0.56) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL19017557 | 1.00 | KDM4E (0.56) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL28495035 | 1.00 | KDM4E (0.56) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL31294925 | 0.91 | LMNA (0.51) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL31294935 | 0.91 | LMNA (0.51) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL31294921 | 0.91 | LMNA (0.51) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL31294936 | 0.91 | LMNA (0.51) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL25477324 | 0.88 | MAPT (0.49) | KDM4EDUSP3MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846880-B2 | Synthetic analogues of phosphatidyl-myo-inositol mannosides with an inhibitory activity of the inflammatory response | Centre National de la Recherche Scientifique—CNRS— (FR) | 2014-09-30 | — | — | US | disclosed |
| EP-2280986-B1 | SYNTHETIC ANALOGUES OF PHOSPHATIDYL-MYO-INOSITOL MANNOSIDES WITH AN INHIBITORY ACTIVITY ON THE INFLAMMATORY RESPONSE | CENTRE NAT RECH SCIENT (FR) | 2013-07-10 | — | — | EP | disclosed |
| US-20110224162-A1 | SYNTHETIC ANALOGUES OF PHOSPHATIDYL-MYO-INOSITOL MANNOSIDES WITH AN INHIBITORY ACTIVITY OF THE INFLAMMATORY RESPONSE | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- (FR) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224162-A1 | SYNTHETIC ANALOGUES OF PHOSPHATIDYL-MYO-INOSITOL MANNOSIDES WITH AN INHIBITORY ACTIVITY OF THE INFLAMMATORY RESPONSE | MIF, MPI, PHOSPHO1 | KDM4E 3938/4885DUSP3 408/4885MEN1 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.