SCHEMBL24210221

SCHEMBL24210221

Fc1ccccc1-c1nc(-c2ccccc2)nc(-c2ccc(-c3ccccc3)cc2)n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.56
RAB9A P51151 5/20 0.56
KMT2A Q03164 4/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
MEN1 O00255 3/20 0.56
NFKB1 P19838 3/20 0.56
NFKB2 Q00653 3/20 0.56
RELA Q04206 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
PKM P14618 2/20 0.56
MAPK1 P28482 2/20 0.56
DPP4 P27487 1/20 0.50
ADORA2A P29274 3/20 0.47
ADORA1 P30542 3/20 0.47
ADORA3 P0DMS8 2/20 0.47
ADORA2B P29275 2/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
MAPT P10636 4/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31658900 1.00 NPC1 (0.56) NPC1RAB9AKMT2AL3MBTL1MEN1
SCHEMBL34465335 1.00 NPC1 (0.56) NPC1RAB9AKMT2AL3MBTL1MEN1
SCHEMBL21461840 0.96 KMT2A (0.59) NPC1RAB9AKMT2AL3MBTL1MEN1
SCHEMBL17827369 0.96 KMT2A (0.59) NPC1RAB9AKMT2AL3MBTL1MEN1
SCHEMBL24417306 0.91 MEN1 (0.49) NPC1RAB9AKMT2AL3MBTL1MEN1
SCHEMBL25987666 0.90 L3MBTL1 (0.54) NPC1RAB9AKMT2AL3MBTL1MEN1
SCHEMBL24450676 0.90 NPC1 (0.58) NPC1RAB9AKMT2AL3MBTL1MEN1
SCHEMBL24417347 0.89 NPC1 (0.50) NPC1RAB9AKMT2AL3MBTL1MEN1
SCHEMBL32690719 0.87 KMT2A (0.51) NPC1RAB9AKMT2AL3MBTL1MEN1
SCHEMBL21461841 0.87 KMT2A (0.51) NPC1RAB9AKMT2AL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024014932-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DIODE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE AND DISPLAY DEVICE 삼성에스디아이 주식회사 2024-01-18 WO disclosed
WO-2023136696-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2023-07-20 WO disclosed
WO-2023128518-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2023-07-06 WO disclosed
WO-2023128529-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2023-07-06 WO disclosed
US-20230123757-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2023-04-20 US disclosed
WO-2022211594-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2022-10-06 WO disclosed
US-20220149289-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2022-05-12 US disclosed
US-20220020933-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2022-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220020933-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OCIAD2, OCIAD1, OXER1 NPC1 1405/4885RAB9A 3109/4885KMT2A 4107/4885
US-20230123757-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OXER1, OCIAD1 NPC1 1239/4885RAB9A 2350/4885KMT2A 4155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.